LiftDNA
LiftDNA helped digital publishers maximize ad revenue by connecting their inventory to multiple demand sources through real-time bidding technology, increasing competition and driving higher CPMs.
Last updated May 11, 2026 by ATDb automated enrichment
- Industry
- Programmatic Advertising / Supply-Side Platform
- Business Model
- Marketplace
- Target Market
- Mid-Market
- Employee Count
- 11-50
- Parent Company
- OpenX
- API Available
- Yes
Early-stage SSP competing in the emerging programmatic marketplace for publisher monetization before being acquired by OpenX in 2012
LiftDNA was a supply-side platform (SSP) founded to help digital publishers optimize their advertising inventory through programmatic selling and real-time bidding (RTB) technology. The platform enabled publishers to connect with multiple demand sources simultaneously, increasing competition for their ad inventory and maximizing yield. LiftDNA positioned itself as a publisher-focused solution in the rapidly growing programmatic advertising ecosystem of the early 2010s. The company operated during a pivotal period in AdTech when SSPs were emerging as critical infrastructure for publishers seeking to move beyond direct sales and traditional ad networks. LiftDNA competed with other early SSPs such as PubMatic, Rubicon Project, and The Rubicon Project, all vying to become the preferred monetization layer for web publishers. Its technology focused on header bidding precursors, auction mechanics, and demand aggregation to drive higher CPMs for its publisher clients. On February 27, 2012, OpenX acquired LiftDNA, integrating its technology and publisher relationships into OpenX's broader ad serving and SSP platform. The acquisition allowed OpenX to strengthen its supply-side capabilities and expand its publisher base. Following the acquisition, LiftDNA ceased to operate as an independent brand and was absorbed into OpenX, which went on to become one of the leading independent SSPs in the programmatic advertising industry.
Supply-Side Platform
Core SSP technology enabling publishers to sell ad inventory programmatically across multiple demand sources
Real-Time Bidding Integration
RTB infrastructure connecting publisher inventory to DSPs and ad exchanges for auction-based selling
Yield Optimization
Tools to help publishers maximize revenue by managing floor prices and demand partner prioritization
- 2008Founded